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RND2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P52198 |
|---|---|
| Clone Names | 101008185 |
| Gene ID | 8153 |
|---|---|
| Other Names | Rho-related GTP-binding protein RhoN, Rho family GTPase 2, Rho-related GTP-binding protein Rho7, Rnd2, RND2, ARHN, RHO7 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RND2 |
|---|---|
| Synonyms | ARHN, RHO7 |
| Function | May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side. Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. |
| Tissue Location | Highly expressed in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the Rho GTPase family, whosemembers play a key role in the regulation of actin cytoskeletonorganization in response to extracellular growth factors. Thisparticular family member has been implicated in the regulation ofneuronal morphology and endosomal trafficking. The gene localizesto chromosome 17 and is the centromeric neighbor of thebreast-ovarian cancer susceptibility gene BRCA1. [provided byRefSeq].
References
Tanaka, H., et al. J. Biol. Chem. 281(15):10355-10364(2006)Kim, Y.S., et al. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 142(4):410-415(2005)Kakimoto, T., et al. J. Biol. Chem. 279(14):14104-14110(2004)Naud, N., et al. Biochem. J. 372 (PT 1), 105-112 (2003) :Fujita, H., et al. J. Biol. Chem. 277(47):45428-45434(2002)
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