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MYBPC3 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q14896
Clone Names 100311159
Peptide ID 100311159
Additional Information
Gene ID 4607
Other Names Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Research Areas
Citations (0)

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MYBPC3 encodes the cardiac isoform of myosin-bindingprotein C. Myosin-binding protein C is a myosin-associated proteinfound in the cross-bridge-bearing zone (C region) of A bands instriated muscle. MYBPC3, the cardiac isoform, is expressedexclussively in heart muscle. Regulatory phosphorylation of thecardiac isoform in vivo by cAMP-dependent protein kinase (PKA) uponadrenergic stimulation may be linked to modulation of cardiaccontraction. Mutations in MYBPC3 are one cause of familialhypertrophic cardiomyopathy.


Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Millat, G., et al. Eur J Med Genet 53(5):261-267(2010)Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)Brion, M., et al. Ann. Clin. Lab. Sci. 40(3):285-289(2010)

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$ 80.00
Cat# BP12436a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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