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RNH1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P13489
Clone Names 100318121
Additional Information
Gene ID 6050
Other Names Ribonuclease inhibitor, Placental ribonuclease inhibitor, Placental RNase inhibitor, Ribonuclease/angiogenin inhibitor 1, RAI, RNH1, PRI, RNH
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNH1
Synonyms PRI, RNH
Function Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.
Cellular Location Cytoplasm.
Research Areas
Citations (0)
citation

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Background

Placental ribonuclease inhibitor (PRI) is a member of afamily of proteinaceous cytoplasmic RNase inhibitors that occur inmany tissues and bind to both intracellular and extracellularRNases (summarized by Lee et al., 1988 [PubMed 3219362]). Inaddition to control of intracellular RNases, the inhibitor may havea role in the regulation of angiogenin (MIM 105850). Ribonucleaseinhibitor, of 50,000 Da, binds to ribonucleases and holds them in alatent form. Since neutral and alkaline ribonucleases probably playa critical role in the turnover of RNA in eukaryotic cells, RNH maybe essential for control of mRNA turnover; the interaction ofeukaryotic cells with ribonuclease may be reversible invivo.

References

Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)Martins-de-Souza, D., et al. J Neural Transm 116(3):275-289(2009)Turcotte, R.F., et al. Biochem. Biophys. Res. Commun. 377(2):512-514(2008)Johnson, R.J., et al. Biochemistry 46(45):13131-13140(2007)Johnson, R.J., et al. J. Mol. Biol. 368(2):434-449(2007)

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$ 277.78
Cat# BP12438b
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