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RASSF10 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession A6NK89
Other Accession NP_001073990.2
Clone Names 100309269
Peptide ID 100309269
Additional Information
Gene ID 644943
Other Names Ras association domain-containing protein 10, RASSF10
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RASSF10
Cellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm
Tissue Location Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70% WHO grade IV primary glioblastomas, but not in grade I astrocytomas.
Research Areas
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Schagdarsurengin, U., et al. Epigenetics 4(8):571-576(2009)Hesson, L.B., et al. Mol. Cancer 8, 42 (2009) :Sherwood, V., et al. Mol. Biol. Cell 19(4):1772-1782(2008)

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$ 80.00
Cat# BP12444c
(40 western blots)
Availability: In Stock
Bulk Size
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