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ZFYVE1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9HBF4
Clone Names 101109065
Peptide ID 101109065
Additional Information
Gene ID 53349
Other Names Zinc finger FYVE domain-containing protein 1, Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1, ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZFYVE1
Synonyms DFCP1, KIAA1589, TAFF1, ZNFN2A1
Cellular Location Golgi apparatus, Golgi stack. Endoplasmic reticulum. Note=Resides predominantly in the cisternal stacks of the Golgi. Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum
Tissue Location Isoform 1 is expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Isoform 1 and isoform 2 are highly expressed in heart. Isoform 2 is also detected in the testis
Research Areas
Citations (0)

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Background

The FYVE domain mediates the recruitment of proteinsinvolved in membrane trafficking and cell signaling tophosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes.This gene encodes a protein which contains two zinc-binding FYVEdomains in tandem. This protein displays a predominantly Golgi,endoplasmic reticulum and vesicular distribution. Alternativelyspliced transcript variants have been found for this gene, and theyencode two isoforms with different sizes.

References

Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)Heilig, R., et al. Nature 421(6923):601-607(2003)Krugmann, S., et al. Mol. Cell 9(1):95-108(2002)Ridley, S.H., et al. J. Cell. Sci. 114 (PT 22), 3991-4000 (2001) :Cheung, P.C., et al. Biochem. J. 355 (PT 1), 113-121 (2001) :

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$ 80.00
Cat# BP12459a
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