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FASTK Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q14296
Clone Names 6021353
Peptide ID 6021353
Additional Information
Gene ID 10922
Other Names Fas-activated serine/threonine kinase, FAST kinase, FASTK
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor.
Tissue Location Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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The protein encoded by this gene is a member of theserine/threonine protein kinase family. This kinase was shown to beactivated rapidly during Fas-mediated apoptosis in Jurkat cells. Inresponse to Fas receptor ligation, it phosphorylates TIA1, anapoptosis-promoting nuclear RNA-binding protein. The encodedprotein is a strong inducer of lymphocyte apoptosis. Two transcriptvariants encoding different isoforms have been found for this gene.Other variants exist, but their full-length natures have not yetbeen determined.


Simarro, M., et al. J. Immunol. 184(9):5325-5332(2010)de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)Simarro, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(27):11370-11375(2007)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Izquierdo, J.M., et al. J. Biol. Chem. 282(3):1539-1543(2007)

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$ 80.00
Cat# BP12464b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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