|Other Names||Syntaxin-2, Epimorphin, STX2, EPIM, STX2A, STX2B, STX2C|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||EPIM, STX2A, STX2B, STX2C|
|Function||Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.|
|Cellular Location||Membrane; Single-pass type IV membrane protein|
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The product of this gene belongs to thesyntaxin/epimorphin family of proteins. The syntaxins are a largeprotein family implicated in the targeting and fusion ofintracellular transport vesicles. The product of this generegulates epithelial-mesenchymal interactions and epithelial cellmorphogenesis and activation. Alternatively spliced transcriptvariants encoding different isoforms have been identified.
Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009)Okugawa, Y., et al. J. Invest. Dermatol. 128(8):1884-1893(2008)Flaumenhaft, R., et al. Blood 110(5):1492-1501(2007)Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)Band, A.M., et al. BMC Cell Biol. 6 (1), 26 (2005) :
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