|Other Names||Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C, STXBP3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.|
|Cellular Location||Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated|
|Tissue Location||Megakaryocytes and platelets.|
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Provided below are standard protocols that you may find useful for product applications.
Together with STX4 and VAMP2, STXBP3 may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity).
Bostrom, P., et al. Diabetes 59(8):1870-1878(2010)Ban, H.J., et al. BMC Genet. 11, 26 (2010) :Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)Smithers, N.P., et al. J. Recept. Signal Transduct. Res. 28(6):581-589(2008)Fu, J., et al. J. Biol. Chem. 280(5):3178-3184(2005)
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