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P2RX4 Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession Q99571
Other Accession NP_002551.2
Additional Information
Gene ID 5025
Other Names P2X purinoceptor 4, P2X4, ATP receptor, Purinergic receptor, P2RX4
Target/Specificity The synthetic peptide sequence is selected from aa 273-287 of HUMAN P2RX4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name P2RX4
Function Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined.


Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wareham, K., et al. Br. J. Pharmacol. 157(7):1215-1224(2009)
Varma, R., et al. Neuromolecular Med. 11(2):63-75(2009)

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$ 80.00
$ 99.00
Cat# BP12490b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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