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ZMIZ2 (PIASz1) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8NF64
Clone Names 2013003
Peptide ID 2013003
Additional Information
Gene ID 83637
Other Names Zinc finger MIZ domain-containing protein 2, PIAS-like protein Zimp7, ZMIZ2, KIAA1886, ZIMP7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1251a was selected from the N-term region of human PIASz. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZMIZ2
Synonyms KIAA1886, ZIMP7
Function Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.
Cellular Location Nucleus. Note=Detected at replication foci throughout S phase
Tissue Location Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary
Research Areas
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PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway. PIAS proteins have been shown to act as transcriptional co-regulators of multiple signaling pathways in various cellular processes. PIASz increases ligand-dependent transcriptional activity of androgen receptor and other nuclear hormone receptors, possibly through alteration of chromatin structure by SWI/SNF-like BAF complexes.

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$ 80.00
Cat# BP1251a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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