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UBTF Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P17480
Clone Names 80924267
Peptide ID 80924267
Additional Information
Gene ID 7343
Other Names Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1, UBTF, UBF, UBF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms UBF, UBF1
Function Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
Cellular Location Nucleus, nucleolus.
Research Areas
Citations (0)

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Upstream binding factor (UBF) is a transcription factorrequired for expression of the 18S, 5.8S, and 28S ribosomal RNAs,along with SL1 (a complex of TBP (MIM 600075) and multipleTBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBFis a nucleolar phosphoprotein with both DNA binding andtransactivation domains. Sequence-specific DNA binding to the coreand upstream control elements of the human rRNA promoter ismediated through several HMG boxes (Jantzen et al., 1990 [PubMed2330041]).


Hisaoka, M., et al. Mol. Cell. Biol. 30(20):4952-4964(2010)Liu, Z., et al. Proteins 77(2):432-447(2009)Lin, C.I., et al. Biochem. Biophys. Res. Commun. 386(2):396-401(2009)Grob, A., et al. J. Cell. Sci. 122 (PT 4), 489-498 (2009) :He, J., et al. Folia Biol. (Praha) 54(6):202-206(2008)

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$ 80.00
Cat# BP12547b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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