|Other Names||UPF0577 protein KIAA1324, Estrogen-induced gene 121 protein, KIAA1324, EIG121|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein|
|Tissue Location||Expressed in normal endometrium but overexpressed in endometroid tumors|
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Provided below are standard protocols that you may find useful for product applications.
K1324 may play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Araki, T., et al. Gene Expr. Patterns 7(6):666-671(2007)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Deng, L., et al. Clin. Cancer Res. 11(23):8258-8264(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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