|Other Names||Bile salt-activated lipase, BAL, Bile salt-stimulated lipase, BSSL, Bucelipase, Carboxyl ester lipase, Cholesterol esterase, Pancreatic lysophospholipase, Sterol esterase, CEL, BAL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.|
|Tissue Location||Mammary gland and pancreas. Expressed by eosinophils.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a glycoproteinsecreted from the pancreas into the digestive tract and from thelactating mammary gland into human milk. The physiological role ofthis protein is in cholesterol and lipid-soluble vitamin esterhydrolysis and absorption. This encoded protein promotes largechylomicron production in the intestine. Also its presence inplasma suggests its interactions with cholesterol and oxidizedlipoproteins to modulate the progression of atherosclerosis. Inpancreatic tumoral cells, this encoded protein is thought to besequestrated within the Golgi compartment and is probably notsecreted. This gene contains a variable number of tandem repeat(VNTR) polymorphism in the coding region that may influence thefunction of the encoded protein.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Torsvik, J., et al. Hum. Genet. 127(1):55-64(2010)McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Li, L., et al. Metab. Clin. Exp. 57(10):1361-1368(2008)
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