Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   KLRC4 Antibody (N-term) Blocking peptide   

KLRC4 Antibody (N-term) Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Primary Accession O43908
Clone Names 100318079
Peptide ID 100318079
Additional Information
Other Names NKG2-F type II integral membrane protein, NK cell receptor F, NKG2-F-activating NK receptor, KLRC4, NKG2F
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLRC4
Synonyms NKG2F
Function May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Natural killer cells. EMBL; U96846; AAC51910.1; -; Genomic_DNA EMBL; U96845; AAC51909.1; -; mRNA EMBL; AF027164; AAC17491.1; -; Genomic_DNA EMBL; AJ001683; CAA04921.1; -; mRNA EMBL; AJ001686; CAA04924.1; -; Genomic_DNA EMBL; AF350018; AAK83805.1; -; mRNA EMBL; AF350019; AAK83806.1; -; mRNA EMBL; AC022075; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC017784; AAH17784.1; -; mRNA CCDS; CCDS8624.1; - RefSeq; NP_038459.1; NM_013431.2 UniGene; Hs.721094; - ProteinModelPortal; O43908; - SMR; O43908; - STRING; 9606.ENSP00000310216; - iPTMnet; O43908; - PhosphoSitePlus; O43908; - BioMuta; KLRC4; - PaxDb; O43908; - PRIDE; O43908; - DNASU; 8302; - Ensembl; ENST00000309384; ENSP00000310216; ENSG00000183542 GeneID; 8302; - KEGG; hsa:8302; - UCSC; uc001qye.4; human CTD; 8302; - DisGeNET; 8302; - GeneCards; KLRC4; - HGNC; HGNC:6377; KLRC4 MIM; 602893; gene neXtProt; NX_O43908; - OpenTargets; ENSG00000183542; - PharmGKB; PA30166; - eggNOG; ENOG410KGBU; Eukaryota eggNOG; ENOG4110SFD; LUCA GeneTree; ENSGT00730000110282; - HOGENOM; HOG000220925; - HOVERGEN; HBG077044; - InParanoid; O43908; - KO; K06541; - OMA; KACDCGH; - OrthoDB; EOG091G0I60; - PhylomeDB; O43908; - BioCyc; ZFISH:ENSG00000121373-MONOMER; - GeneWiki; KLRC4; - GenomeRNAi; 8302; - PRO; PR:O43908; - Proteomes; UP000005640; Chromosome 12 Bgee; ENSG00000183542; - Genevisible; O43908; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0006968; P:cellular defense response; TAS:ProtInc Gene3D; 3.10.100.10; -; 1 InterPro; IPR016186; C-type_lectin-like/link InterPro; IPR016187; CTDL_fold SUPFAM; SSF56436; SSF56436; 1 2: Evidence at transcript level; Complete proteome; Disulfide bond; Membrane; Polymorphism; Receptor; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix CHAIN 1 158 NKG2-F type II integral membrane protein /FTId=PRO_0000046673 TOPO_DOM 1 74 Cytoplasmic. TRANSMEM 75 95 Helical; Signal-anchor for type II membrane protein. TOPO_DOM 96 158 Extracellular. VARIANT 29 29 I -> S (in allele NKG2-F*02; dbSNP:rs1841958) /FTId=VAR_013406 VARIANT 104 104 N -> S (in allele NKG2-F*02; dbSNP:rs2617170) /FTId=VAR_013407 SEQUENCE 158 AA; 18234 MW; 1AABC0E5ED26ACCC CRC64; MNKQRGTYSE VSLAQDPKRQ QRKLKGNKIS ISGTKQEIFQ VELNLQNASS DHQGNDKTYH CKGLLPPPEK LTAEVLGIIC IVLMATVLKT IVLIPCIGVL EQNNFSLNRR MQKARHCGHC PEEWITYSNS CYYIGKERRT WEERVCWPVL RRTLICFL
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

Background

Natural killer (NK) cells are lymphocytes that can mediatelysis of certain tumor cells and virus-infected cells withoutprevious activation. They can also regulate specific humoral andcell-mediated immunity. NK cells preferentially express severalcalcium-dependent (C-type) lectins, which have been implicated inthe regulation of NK cell function. KLRC4 is a member of the NKG2group which are expressed primarily in natural killer (NK) cellsand encodes a family of transmembrane proteins characterized by atype II membrane orientation (extracellular C terminus) and thepresence of a C-type lectin domain. The NKG2 gene family is locatedwithin the NK complex, a region that contains several C-type lectingenes preferentially expressed on NK cells. The 3' end of the KLRC4transcript includes the first non-coding exon found at the 5' endof the adjacent D12S2489E gene transcript.

References

Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Ma, J., et al. J. Med. Virol. 82(9):1501-1507(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Sellick, G.S., et al. Blood 111(3):1625-1633(2008)Cao, Q., et al. Zhonghua Nei Ke Za Zhi 45(10):824-826(2006)

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 80.00
Cat# BP12559a
Size:
Quantity:
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
30% off on 2,800+ Neuroscience Antibodies. PromoCode:<span class=text-red> FLASH20
Terms & Conditions