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CYFIP2 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96F07
Clone Names 100318122
Peptide ID 100318122
Additional Information
Gene ID 26999
Other Names Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121, CYFIP2 {ECO:0000312|EMBL:AAH117621}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYFIP2 {ECO:0000312|EMBL:AAH11762.1}
Function Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA.
Cellular Location Cytoplasm. Nucleus. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q5SQX6}. Cell junction, synapse, synaptosome {ECO:0000250|UniProtKB:Q5SQX6}. Note=Highly expressed in the perinuclear regionand enriched in synaptosomes (By similarity). Treatment with leptomycin-B triggers translocation to the nucleus (PubMed:17245118). {ECO:0000250|UniProtKB:Q5SQX6, ECO:0000269|PubMed:17245118}
Tissue Location Expressed in T-cells. Increased expression is observed in CD4(+) T-lymphocytes from patients with multiple sclerosis (at protein level).
Research Areas
Citations (0)

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Background

CYFIP2 is involved in T-cell adhesion and TP53/p53-dependent induction of apoptosis. Does not bind RNA.

References

Anitei, M., et al. Nat. Cell Biol. 12(4):330-340(2010)Wu, H., et al. J. Allergy Clin. Immunol. 125(2):321-327(2010)Daley, D., et al. Hum. Genet. 125(4):445-459(2009)Zhou, H., et al. BMC Med. Genet. 10, 123 (2009) :Jackson, R.S. II, et al. Cell Cycle 6(1):95-103(2007)

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$ 80.00
Cat# BP12564c
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