|Other Names||Tubulin polyglutamylase TTLL4, 6---, Tubulin--tyrosine ligase-like protein 4, TTLL4, KIAA0173|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Polyglutamylase which preferentially modifies beta- tubulin and nucleosome assembly proteins NAP1 and NAP2. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity).|
|Cellular Location||Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body Note=Located in cilia. In some cells, also found in basal bodies (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
TTLL4 is polyglutamylase which preferentially modifies beta-tubulin and nucleosome assembly proteins NAP1 and NAP2. It is involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity).
Trichet, V., et al. Gene 257(1):109-117(2000)
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