FAM150A Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6UXT8 |
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Clone Names | 100203079 |
Gene ID | 389658 |
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Other Names | Protein FAM150A, FAM150A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ALKL1 |
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Function | Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation (PubMed:25331893, PubMed:26418745, PubMed:26630010, PubMed:34646012, PubMed:34819673). Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation (PubMed:34646012, PubMed:34819673). In contrast to ALKAL2, does not act as a potent physiological ligand for ALK (PubMed:26418745, PubMed:34646012). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q6UX46}. Cell membrane. Note=Following interaction with receptor tyrosine kinase LTK, associates with the cell membrane, membrane-binding is required to activate LTK {ECO:0000250|UniProtKB:Q6UX46} |
Tissue Location | Widely expressed with highest levels in thyroid and moderate levels in stomach, trachea, small intestine, prostate and brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The exact functions of this protein remain unknown.
References
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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