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FAM150A Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6UXT8
Clone Names 100203079
Additional Information
Gene ID 389658
Other Names Protein FAM150A, FAM150A
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALKL1
Function Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation (PubMed:25331893, PubMed:26418745, PubMed:26630010, PubMed:34646012, PubMed:34819673). Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation (PubMed:34646012, PubMed:34819673). In contrast to ALKAL2, does not act as a potent physiological ligand for ALK (PubMed:26418745, PubMed:34646012).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q6UX46}. Cell membrane. Note=Following interaction with receptor tyrosine kinase LTK, associates with the cell membrane, membrane-binding is required to activate LTK {ECO:0000250|UniProtKB:Q6UX46}
Tissue Location Widely expressed with highest levels in thyroid and moderate levels in stomach, trachea, small intestine, prostate and brain.
Research Areas
Citations (0)
citation

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Background

The exact functions of this protein remain unknown.

References

Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 277.78
Cat# BP12588c
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