|Other Names||NAD-dependent malic enzyme, mitochondrial, NAD-ME, Malic enzyme 2, ME2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Mitochondrion matrix.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a mitochondrial NAD-dependent malicenzyme, a homotetrameric protein, that catalyzes the oxidativedecarboxylation of malate to pyruvate. It had previously beenweakly linked to a syndrome known as Friedreich ataxia that hassince been shown to be the result of mutation in a completelydifferent gene. Certain single-nucleotide polymorphism haplotypesof this gene have been shown to increase the risk for idiopathicgeneralized epilepsy. Alternatively spliced transcript variantsencoding different isoforms found for this gene. [provided byRefSeq].
MacDonald, M.J., et al. Arch. Biochem. Biophys. 488(2):100-104(2009)French, D., et al. Blood 113(19):4512-4520(2009)Escamilla, M. Pharmacogenomics 8(7):691-695(2007)Chou, W.Y., et al. Biochem. Biophys. Res. Commun. 357(1):133-138(2007)Lenzen, K.P., et al. Epilepsia 46(10):1637-1641(2005)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.