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MGAT4C Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UBM8
Clone Names 100324002
Peptide ID 100324002
Additional Information
Gene ID 25834
Other Names Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C, N-acetylglucosaminyltransferase IV homolog, hGnT-IV-H, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc, GlcNAc-T IVc, GnT-IVc, N-acetylglucosaminyltransferase IVc, UDP-N-acetylglucosamine: alpha-1, 3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase IVc, MGAT4C
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MGAT4C
Function Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas
Research Areas
Citations (0)

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Background

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri-and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :Trynka, G., et al. Gut 58(8):1078-1083(2009)Furukawa, T., et al. J. Hum. Genet. 44(6):397-401(1999)Thomas, B.A. Br. J. Dermatol. 80 (6), 413 (1968) :

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$ 80.00
Cat# BP12619b
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