|Other Names||Cytochrome P450 2S1, CYPIIS1, CYP2S1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Has a potential importance for extrahepatic xenobiotic metabolism.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein|
|Tissue Location||High level of expression in trachea, lung, stomach, small intestine, and spleen|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum. In rodents,the homologous protein has been shown to metabolize certaincarcinogens; however, the specific function of the human proteinhas not been determined.
Bui, P.H., et al. Mol. Pharmacol. 76(5):1031-1043(2009)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Deb, S., et al. Expert Opin Drug Metab Toxicol 5(4):367-380(2009)Jang, Y.J., et al. Ther Drug Monit 29(3):292-298(2007)Hanzawa, Y., et al. Drug Metab. Pharmacokinet. 22(2):136-140(2007)
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