|Other Names||CCAAT/enhancer-binding protein delta, C/EBP delta, Nuclear factor NF-IL6-beta, NF-IL6-beta, CEBPD|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this intronless gene is a bZIPtranscription factor which can bind as a homodimer to certain DNAregulatory regions. It can also form heterodimers with the relatedprotein CEBP-alpha. The encoded protein is important in theregulation of genes involved in immune and inflammatory responses,and may be involved in the regulation of genes associated withactivation and/or differentiation of macrophages. The cytogeneticlocation of this locus has been reported as both 8p11 and 8q11.
Zannetti, C., et al. J. Biol. Chem. 285(45):34773-34780(2010)Wang, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16131-16136(2010)Hour, T.C., et al. Biochem. Pharmacol. 80(3):325-334(2010)Bennett, C.E., et al. Diab Vasc Dis Res 7(3):195-203(2010)Payne, V.A., et al. Biochem. J. 425(1):215-223(2010)
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