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PLOD1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q02809
Clone Names 100318020
Peptide ID 100318020
Additional Information
Gene ID 5351
Other Names Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1, Lysyl hydroxylase 1, LH1, PLOD1, LLH, PLOD
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLOD1
Synonyms LLH, PLOD
Function Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Cellular Location Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side
Research Areas
Citations (0)

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Lysyl hydroxylase is a membrane-bound homodimeric proteinlocalized to the cisternae of the endoplasmic reticulum. The enzyme(cofactors iron and ascorbate) catalyzes the hydroxylation of lysylresidues in collagen-like peptides. The resultant hydroxylysylgroups are attachment sites for carbohydrates in collagen and thusare critical for the stability of intermolecular crosslinks. Somepatients with Ehlers-Danlos syndrome type VI have deficiencies inlysyl hydroxylase activity.


Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Huang, Q.Y., et al. Bone 44(5):984-988(2009)Yamada, Y., et al. Int. J. Mol. Med. 19(5):791-801(2007)Tasker, P.N., et al. Osteoporos Int 17(7):1078-1085(2006)Giunta, C., et al. Mol. Genet. Metab. 86 (1-2), 269-276 (2005) :

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$ 80.00
Cat# BP12656c
(40 western blots)
Availability: In Stock
Bulk Size
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