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APBA2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q99767
Clone Names 100318014
Peptide ID 100318014
Additional Information
Gene ID 321
Other Names Amyloid beta A4 precursor protein-binding family A member 2, Adapter protein X11beta, Neuron-specific X11L protein, Neuronal Munc18-1-interacting protein 2, Mint-2, APBA2, MINT2, X11L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name APBA2
Synonyms MINT2, X11L
Function Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
Tissue Location Brain.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the X11protein family. It is a neuronal adapter protein that interactswith the Alzheimer's disease amyloid precursor protein (APP). Itstabilizes APP and inhibits production of proteolytic APP fragmentsincluding the A beta peptide that is deposited in the brains ofAlzheimer's disease patients. This gene product is believed to beinvolved in signal transduction processes. It is also regarded as aputative vesicular trafficking protein in the brain that can form acomplex with the potential to couple synaptic vesicle exocytosis toneuronal cell adhesion. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Swistowski, A., et al. J. Neurosci. 29(50):15703-15712(2009)Mitchell, J.C., et al. Hum. Mol. Genet. 18(23):4492-4500(2009)Babatz, T.D., et al. Autism Res 2(6):359-364(2009)Chang, S.J., et al. BMC Genomics 10, 613 (2009) :

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$ 80.00
Cat# BP12659c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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