|Other Names||Amyloid beta A4 precursor protein-binding family A member 2, Adapter protein X11beta, Neuron-specific X11L protein, Neuronal Munc18-1-interacting protein 2, Mint-2, APBA2, MINT2, X11L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the X11protein family. It is a neuronal adapter protein that interactswith the Alzheimer's disease amyloid precursor protein (APP). Itstabilizes APP and inhibits production of proteolytic APP fragmentsincluding the A beta peptide that is deposited in the brains ofAlzheimer's disease patients. This gene product is believed to beinvolved in signal transduction processes. It is also regarded as aputative vesicular trafficking protein in the brain that can form acomplex with the potential to couple synaptic vesicle exocytosis toneuronal cell adhesion. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Swistowski, A., et al. J. Neurosci. 29(50):15703-15712(2009)Mitchell, J.C., et al. Hum. Mol. Genet. 18(23):4492-4500(2009)Babatz, T.D., et al. Autism Res 2(6):359-364(2009)Chang, S.J., et al. BMC Genomics 10, 613 (2009) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.