|Other Names||Adipolin, Adipose-derived insulin-sensitizing factor, Complement C1q tumor necrosis factor-related protein 12, Adipolin fCTRP12, Adipolin full-length form, Adipolin gCTRP12, Adipolin cleaved form, FAM132A, C1QDC2, CTRP12|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue (By similarity).|
|Cellular Location||Adipolin fCTRP12: Secreted.|
|Tissue Location||Predominantly expressed by adipose tissues.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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