|Other Names||Probable phospholipid-transporting ATPase VD, ATPase class V type 10D, P4-ATPase flippase complex alpha subunit ATP10D, ATP10D, ATPVD, KIAA1487|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B|
|Tissue Location||Expressed in placenta and, to a lesser extent, in kidney.|
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The exact function of ATP10D remains unknown.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Hicks, A.A., et al. PLoS Genet. 5 (10), E1000672 (2009) :Flamant, S., et al. Mamm. Genome 14(1):21-30(2003)
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