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MAT1A Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q00266
Clone Names 100318171
Peptide ID 100318171
Additional Information
Gene ID 4143
Other Names S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1, Methionine adenosyltransferase I/III, MAT-I/III, MAT1A, AMS1, MATA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAT1A
Synonyms AMS1, MATA1
Function Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
Tissue Location Expressed in liver.
Research Areas
Citations (0)

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Background

This gene catalyzes a two-step reaction that involves thetransfer of the adenosyl moiety of ATP to methionine to formS-adenosylmethionine and tripolyphosphate, which is subsequentlycleaved to PPi and Pi. S-adenosylmethionine is the source of methylgroups for most biological methylations. The encoded protein isfound as a homotetramer (MAT I) or a homodimer (MAT III) whereas athird form, MAT II (gamma), is encoded by the MAT2A gene. Mutationsin this gene are associated with methionine adenosyltransferasedeficiency.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Wu, S.M., et al. Cell. Mol. Life Sci. 67(11):1831-1843(2010)Lai, C.Q., et al. Am. J. Clin. Nutr. 91(5):1377-1386(2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 80.00
Cat# BP12704a
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