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MAT1A Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q00266 |
|---|---|
| Clone Names | 100318171 |
| Gene ID | 4143 |
|---|---|
| Other Names | S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1, Methionine adenosyltransferase I/III, MAT-I/III, MAT1A, AMS1, MATA1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MAT1A |
|---|---|
| Synonyms | AMS1, MATA1 |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Tissue Location | Expressed in liver.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene catalyzes a two-step reaction that involves thetransfer of the adenosyl moiety of ATP to methionine to formS-adenosylmethionine and tripolyphosphate, which is subsequentlycleaved to PPi and Pi. S-adenosylmethionine is the source of methylgroups for most biological methylations. The encoded protein isfound as a homotetramer (MAT I) or a homodimer (MAT III) whereas athird form, MAT II (gamma), is encoded by the MAT2A gene. Mutationsin this gene are associated with methionine adenosyltransferasedeficiency.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Wu, S.M., et al. Cell. Mol. Life Sci. 67(11):1831-1843(2010)Lai, C.Q., et al. Am. J. Clin. Nutr. 91(5):1377-1386(2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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