|Other Names||ATP-binding cassette sub-family G member 4, ABCG4, WHITE2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in macrophage lipid homeostasis.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in brain tissues with the exception of the spinal cord.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is included in thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the White subfamily and is expressedpredominantly in liver tissue. The function has not yet beendetermined but may involve cholesterol transport. Alternate splicevariants have been described but their full length sequences havenot been determined.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Koshiba, S., et al. Xenobiotica 38 (7-8), 863-888 (2008) :
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