DNAJC27 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NZQ0 |
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Clone Names | 101008012 |
Gene ID | 51277 |
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Other Names | DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein, DNAJC27, RABJS, RBJ |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DNAJC27 |
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Synonyms | RABJS, RBJ |
Function | GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8CFP6}. |
Tissue Location | Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the small GTPase superfamily. Rab family. 3 isoforms.
References
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Nepomuceno-Silva, J.L., et al. Gene 327(2):221-232(2004)
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