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CTSO Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P43234 |
|---|---|
| Clone Names | 80513085 |
| Gene ID | 1519 |
|---|---|
| Other Names | Cathepsin O, CTSO, CTSO1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CTSO |
|---|---|
| Synonyms | CTSO1 |
| Function | Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. |
| Cellular Location | Lysosome. |
| Tissue Location | Expressed in all tissues examined. High levels seen in the ovary, kidney and placenta while low levels seen in thymus and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by the gene is a cysteine proteinaseand a member of the papain superfamily. This proteolytic enzyme isinvolved in cellular protein degradation and turnover. Therecombinant form of this enzyme was shown to degrade syntheticpeptides typically used as substrates for cysteine proteinases andits proteolytic activity was abolished by an inhibitor of cyteineproteinase.
References
Roeske, D., et al. Mol. Psychiatry (2009) In press :Lamesch, P., et al. Genomics 89(3):307-315(2007)Santamaria, I., et al. Genomics 53(2):231-234(1998)Shi, G.P., et al. FEBS Lett. 357(2):129-134(1995)Velasco, G., et al. J. Biol. Chem. 269(43):27136-27142(1994)
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