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SPOPL Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6IQ16
Clone Names 91201289
Additional Information
Gene ID 339745
Other Names Speckle-type POZ protein-like, HIB homolog 2, Roadkill homolog 2, SPOPL
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPOPL
Function Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin- protein ligase complexes that contain SPOP.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

In complex with a cullin, may act in ubiquitination and proteasomal degradation processes (By similarity).

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)Zhang, Q., et al. Dev. Cell 10(6):719-729(2006)Kent, D., et al. Development 133(10):2001-2010(2006)

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$ 277.78
Cat# BP12768c
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