|Other Names||60S ribosomal protein L15, RPL15, EC45|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Lipid-anchor|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L15E family of ribosomal proteins. It is located in thecytoplasm. This gene shares sequence similarity with the yeastribosomal protein YL10 gene. Although this gene has been referredto as RPL10, its official symbol is RPL15. This gene has been shownto be overexpressed in some esophageal tumors compared to normalmatched tissues. Transcript variants utilizing alternative polyAsignals exist. As is typical for genes encoding ribosomal proteins,there are multiple processed pseudogenes of this gene dispersedthrough the genome.
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :Wang, H., et al. BMC Cancer 6, 91 (2006) :Andersen, J.S., et al. Nature 433(7021):77-83(2005)Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :Mazumder, B., et al. Cell 115(2):187-198(2003)
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