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UBAP2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5T6F2
Clone Names 91102050
Additional Information
Gene ID 55833
Other Names Ubiquitin-associated protein 2, UBAP-2, UBAP2 {ECO:0000312|EMBL:AAI117631}
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBAP2 {ECO:0000312|EMBL:AAI11763.1}
Function Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage (PubMed:35633597). May promote the degradation of ANXA2 (PubMed:27121050).
Cellular Location Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin
Research Areas
Citations (0)
citation

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Background

This gene is a novel gene isolated based on its expressionin the human adrenal gland. The full-length protein encoded by thisgene contains a UBA-domain (ubiquitin associated domain), which isa motif found in several proteins having connections to ubiquitinand the ubiquitination pathway. In addition, the protein contains aregion similar to a domain found in members of the atrophin-1family. The function of this protein has not been determined.Additional alternate splice variants may exist, but their fulllength nature has not been determined.

References

Venturelli, E., et al. Neurosci. Lett. 482(3):240-244(2010)Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) :Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)

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$ 277.78
Cat# BP12773a
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