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GABRA6 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q16445
Clone Names 100318074
Additional Information
Gene ID 2559
Other Names Gamma-aminobutyric acid receptor subunit alpha-6, GABA(A) receptor subunit alpha-6, GABRA6
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GABRA6
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Cellular Location Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

GABA is the major inhibitory neurotransmitter in themammalian brain where it acts at GABA-A receptors, which areligand-gated chloride channels. Chloride conductance of thesechannels can be modulated by agents such as benzodiazepines thatbind to the GABA-A receptor. At least 16 distinct subunits ofGABA-A receptors have been identified.

References

Green, E.K., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :Duncan, C.E., et al. J Psychiatr Res 44(10):673-681(2010)Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :Pham, X., et al. Depress Anxiety 26(11):998-1003(2009)

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$ 277.78
Cat# BP12781b
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