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NFKBIL1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UBC1
Clone Names 100311258
Additional Information
Gene ID 4795
Other Names NF-kappa-B inhibitor-like protein 1, Inhibitor of kappa B-like protein, I-kappa-B-like protein, IkappaBL, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1, NFKBIL1, IKBL
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NFKBIL1
Synonyms IKBL
Function Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.
Cellular Location Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus
Tissue Location Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes
Research Areas
Citations (0)
citation

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Background

This gene encodes a divergent member of the I-kappa-Bfamily of proteins. Its function has not been determined. The genelies within the major histocompatibility complex (MHC) class Iregion on chromosome 6. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].

References

Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Owecki, M.K., et al. Pol. Merkur. Lekarski 28(167):366-370(2010)

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$ 277.78
Cat# BP12802b
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