|Other Names||40S ribosomal protein S4, Y isoform 1, RPS4Y1, RPS4Y|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Cytoplasmic ribosomes, organelles that catalyze proteinsynthesis, consist of a small 40S subunit and a large 60S subunit.Together these subunits are composed of 4 RNA species andapproximately 80 structurally distinct proteins. This gene encodesribosomal protein S4, a component of the 40S subunit. Ribosomalprotein S4 is the only ribosomal protein known to be encoded bymore than one gene, namely this gene and ribosomal protein S4,X-linked (RPS4X). The 2 isoforms encoded by these genes are notidentical, but are functionally equivalent. Ribosomal protein S4belongs to the S4E family of ribosomal proteins. It has beensuggested that haploinsufficiency of the ribosomal protein S4 genesplays a role in Turner syndrome; however, this hypothesis iscontroversial. As is typical for genes encoding ribosomal proteins,there are multiple processed pseudogenes of this gene dispersedthrough the genome.
Agate, R.J., et al. Mol. Biol. Evol. 21(2):384-396(2004)Vawter, M.P., et al. Neuropsychopharmacology 29(2):373-384(2004)Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :Skaletsky, H., et al. Nature 423(6942):825-837(2003)Sampath, P., et al. Mol. Cell. Biol. 23(5):1509-1519(2003)
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