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TNP2 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q05952
Clone Names 100324076
Peptide ID 100324076
Additional Information
Gene ID 7142
Other Names Nuclear transition protein 2, TP-2, TP2, TNP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNP2
Function In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.
Cellular Location Nucleus, nucleolus {ECO:0000250|UniProtKB:P11101}. Chromosome {ECO:0000250|UniProtKB:P11101}. Note=Nuclear import is ATP- dependent and nucleolar localization requires the protein to be phosphorylated. {ECO:0000250|UniProtKB:P11101}
Tissue Location Expressed by spermatids (at protein level).
Research Areas
Citations (0)

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Background

In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.

References

Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)Khattri, A., et al. Int. J. Androl. (2010) In press :Pradeepa, M.M., et al. J. Biol. Chem. 284(43):29956-29967(2009)Cooper, J.D., et al. Nat. Genet. 40(12):1399-1401(2008)Becker, S., et al. Andrologia 40(4):203-208(2008)

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$ 80.00
Cat# BP12809b
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