|Other Names||Synaptotagmin-like protein 1, Exophilin-7, Protein JFC1, SYTL1, SLP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes|
|Tissue Location||Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).|
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SYTL1 may play a role in vesicle trafficking (By similarity). It binds phosphatidylinositol 3,4,5-triphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).
Neumuller, O., et al. Blood 114(7):1396-1404(2009)Holt, O., et al. Traffic 9(4):446-457(2008)Schmid, M., et al. J. Leukoc. Biol. 81(4):907-915(2007)Johnson, J.L., et al. Biochem. J. 391 (PT 3), 699-710 (2005) :Catz, S.D., et al. Biochem. J. 367 (PT 3), 791-799 (2002) :
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