C22orf28 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y3I0 |
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Other Accession | NP_055121.1 |
Clone Names | 100405090 |
Gene ID | 51493 |
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Other Names | tRNA-splicing ligase RtcB homolog {ECO:0000255|HAMAP-Rule:MF_03144}, 6513 {ECO:0000255|HAMAP-Rule:MF_03144}, RTCB {ECO:0000255|HAMAP-Rule:MF_03144}, C22orf28 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RTCB {ECO:0000255|HAMAP-Rule:MF_03144} |
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Synonyms | C22orf28 |
Function | Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. |
Cellular Location | Nucleus. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03144, ECO:0000269|PubMed:24608264} Note=Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low |
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Provided below are standard protocols that you may find useful for product applications.
References
Guo, D., et al. Biochem. Biophys. Res. Commun. 337(4):1308-1318(2005)de Hoog, C.L., et al. Cell 117(5):649-662(2004)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Collins, J.E., et al. Genome Res. 13(1):27-36(2003)Hu, R.M., et al. Proc. Natl. Acad. Sci. U.S.A. 97(17):9543-9548(2000)
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