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LOXL3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P58215
Clone Names 100405149
Peptide ID 100405149
Additional Information
Gene ID 84695
Other Names Lysyl oxidase homolog 3, 143-, Lysyl oxidase-like protein 3, LOXL3, LOXL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LOXL3
Synonyms LOXL
Function Both isoforms function as amine oxidases toward elastin and different types of collagens. Isoform 1 shows the highest activity toward collagen type VIII, while Isoform 2 presents the highest activity toward collagen type IV.
Cellular Location Isoform 1: Secreted, extracellular space
Tissue Location Isoform 1 ia predominantly detected in the heart, placenta, lung, and small intestine, while isoform 2 is more highly detected in the kidney, pancreas, spleen, and thymus, and is absent in lung.
Research Areas
Citations (0)

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This gene encodes a member of the lysyl oxidase genefamily. The prototypic member of the family is essential to thebiogenesis of connective tissue, encoding an extracellularcopper-dependent amine oxidase that catalyses the first step in theformation of crosslinks in collagens and elastin. A highlyconserved amino acid sequence at the C-terminus end appears to besufficient for amine oxidase activity, suggesting that each familymember may retain this function. The N-terminus is poorly conservedand may impart additional roles in developmental regulation,senescence, tumor suppression, cell growth control, and chemotaxisto each member of the family. Alternatively spliced transcriptvariants of this gene have been reported but their full-lengthnature has not been determined.


Kim, Y., et al. Oncol. Rep. 22(4):799-804(2009)Sebban, S., et al. Virchows Arch. 454(1):71-79(2009)Akagawa, H., et al. Hum. Genet. 121 (3-4), 377-387 (2007) :Lee, J.E., et al. J. Biol. Chem. 281(49):37282-37290(2006)Peinado, H., et al. EMBO J. 24(19):3446-3458(2005)

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$ 80.00
Cat# BP12837b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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