|Other Names||Mitochondrial import inner membrane translocase subunit TIM44, TIMM44, MIMT44, TIM44|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.|
|Cellular Location||Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix|
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Provided below are standard protocols that you may find useful for product applications.
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Martins-de-Souza, D., et al. J Psychiatr Res (2010) In press :Yuryev, A., et al. Genomics 81(2):112-125(2003)Yuryev, A., et al. Mol. Cell. Biol. 20(13):4870-4878(2000)Moro, F., et al. EMBO J. 18(13):3667-3675(1999)Bauer, M.F., et al. J. Mol. Biol. 289(1):69-82(1999)
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