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PIK3AP1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6ZUJ8
Clone Names 100405226
Peptide ID 100405226
Additional Information
Gene ID 118788
Other Names Phosphoinositide 3-kinase adapter protein 1, B-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, BCAP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PIK3AP1
Synonyms BCAP
Function Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein
Tissue Location Expressed in natural killer (NK) cells.
Research Areas
Citations (0)

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PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).


Koutros, S., et al. Cancer Res. 70(6):2389-2396(2010)Rikova, K., et al. Cell 131(6):1190-1203(2007)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Maruoka, M., et al. FEBS Lett. 579(14):2986-2990(2005)Okada, T., et al. Immunity 13(6):817-827(2000)

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$ 80.00
Cat# BP12861b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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