|Other Names||SLAM family member 8, B-lymphocyte activator macrophage expressed, BCM-like membrane protein, CD353, SLAMF8, BLAME|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in lymph node, spleen, thymus and bone marrow.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the CD2 family of cellsurface proteins involved in lymphocyte activation. These proteinsare characterized by Ig domains. This protein is expressed inlymphoid tissues, and studies of a similar protein in mouse suggestthat it may function during B cell lineage commitment. The gene isfound in a region of chromosome 1 containing many CD2 genes.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)Tangye, S.G., et al. J. Immunol. 171(5):2485-2495(2003)Kingsbury, G.A., et al. J. Immunol. 166(9):5675-5680(2001)
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