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CPN1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P15169
Clone Names 80410142
Peptide ID 80410142
Additional Information
Gene ID 1369
Other Names Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, Serum carboxypeptidase N, SCPN, CPN1, ACBP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPN1
Synonyms ACBP
Function Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Cellular Location Secreted, extracellular space.
Tissue Location Synthesized in the liver and secreted in plasma
Research Areas
Citations (0)

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Carboxypeptidase N is a plasma metallo-protease thatcleaves basic amino acids from the C terminal of peptides andproteins. The enzyme is important in the regulation of peptideslike kinins and anaphylatoxins, and has also been known askininase-1 and anaphylatoxin inactivator. This enzyme is a tetramercomprised of two identical regulatory subunits and two identicalcatalytic subunits; this gene encodes the catalytic subunit.Mutations in this gene can be associated with angioedema or chronicurticaria resulting from carboxypeptidase N deficiency. [providedby RefSeq].


Speliotes, E.K., et al. Hepatology 52(3):904-912(2010)Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)Du, X.Y., et al. J. Biol. Chem. 284(2):751-758(2009)Yuan, X., et al. Am. J. Hum. Genet. 83(4):520-528(2008)Skidgel, R.A., et al. Int. Immunopharmacol. 7(14):1888-1899(2007)

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$ 80.00
Cat# BP12882c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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