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DCTN2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q13561
Clone Names 81006075
Peptide ID 81006075
Additional Information
Gene ID 10540
Other Names Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin, DCTN2, DCTN50
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCTN2
Synonyms DCTN50
Function Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Membrane; Peripheral membrane protein
Research Areas
Citations (0)

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This gene encodes a 50-kD subunit of dynactin, amacromolecular complex consisting of 10-11 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation, chromosomemovement, nuclear positioning, and axonogenesis. This subunit ispresent in 4-5 copies per dynactin molecule. It contains threeshort alpha-helical coiled-coil domains that may mediateassociation with self or other dynactin subunits. It may interactdirectly with the largest subunit (p150) of dynactin and may affixp150 in place.


Jacquot, G., et al. J. Biol. Chem. 285(30):23019-23031(2010)Inoue, M., et al. Genes Cells 13(8):905-914(2008)Maier, K.C., et al. Traffic 9(4):481-491(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Camargo, L.M., et al. Mol. Psychiatry 12(1):74-86(2007)

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$ 80.00
Cat# BP12893c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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