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BCAT2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O15382 |
|---|---|
| Clone Names | 80924079 |
| Gene ID | 587 |
|---|---|
| Other Names | Branched-chain-amino-acid aminotransferase, mitochondrial, BCAT(m), Placental protein 18, PP18, BCAT2, BCATM, BCT2, ECA40 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BCAT2 |
|---|---|
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine (PubMed:8702755, PubMed:25653144, PubMed:17050531). May also function as a transporter of branched chain alpha-keto acids (By similarity). |
| Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:O35854}. |
| Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a branched chain aminotransferase foundin mitochondria. The encoded protein forms a dimer that catalyzesthe first step in the production of the branched chain amino acidsleucine, isoleucine, and valine. Multiple transcript variantsencoding different isoforms have been found for this gene.
References
Coles, S.J., et al. Biochemistry 48(3):645-656(2009)Yennawar, N.H., et al. J. Biol. Chem. 281(51):39660-39671(2006)Goto, M., et al. J. Biol. Chem. 280(44):37246-37256(2005)Conway, M.E., et al. Biochemistry 43(23):7356-7364(2004)Yennawar, N., et al. Acta Crystallogr. D Biol. Crystallogr. 57 (PT 4), 506-515 (2001) :
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