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GLO1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q04760 |
|---|---|
| Clone Names | 81020121 |
| Gene ID | 2739 |
|---|---|
| Other Names | Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase, GLO1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GLO1 |
|---|---|
| Function | Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:9705294, PubMed:23122816). Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (PubMed:19199007). Required for normal osteoclastogenesis (By similarity). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The enzyme encoded by this gene is responsible for thecatalysis and formation of S-lactoyl-glutathione from methylglyoxalcondensation and reduced glutatione. Glyoxalase I is linked to HLAand is localized to 6p21.3-p21.1, between HLA and the centromere.
References
Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)Naidu, R., et al. Pathol. Int. 60(9):614-620(2010)Santarius, T., et al. Genes Chromosomes Cancer 49(8):711-725(2010)Kovanen, L., et al. Alcohol Alcohol. 45(4):303-311(2010)Krechler, T., et al. Clin. Biochem. 43 (10-11), 882-886 (2010) :
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