|Other Names||Elongation factor Tu, mitochondrial, EF-Tu, P43, TUFM|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.|
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This gene encodes a protein which participates in proteintranslation in mitochondria. Mutations in this gene have beenassociated with combined oxidative phosphorylation deficiencyresulting in lactic acidosis and fatal encephalopathy. A pseudogenehas been identified on chromosome 17.
Valente, L., et al. Biochim. Biophys. Acta 1792(8):791-795(2009)Sasarman, F., et al. Hum. Mol. Genet. 17(23):3697-3707(2008)Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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