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HMBS Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P08397
Clone Names 90121163
Peptide ID 90121163
Additional Information
Gene ID 3145
Other Names Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase, HMBS, PBGD, UPS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PBGD, UPS
Function Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Cellular Location Cytoplasm.
Tissue Location Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells.
Research Areas
Citations (0)

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This gene encodes a member of the hydroxymethylbilanesynthase superfamily. The encoded protein is the third enzyme ofthe heme biosynthetic pathway and catalyzes the head to tailcondensation of four porphobilinogen molecules into the linearhydroxymethylbilane. Mutations in this gene are associated with theautosomal dominant disease acute intermittent porphyria.Alternatively spliced transcript variants encoding differentisoforms have been described.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Surin, V.L., et al. Genetika 46(4):540-552(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Gill, R., et al. Biochem. J. 420(1):17-25(2009)Ulbrichova, D., et al. FEBS J. 276(7):2106-2115(2009)

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$ 80.00
Cat# BP12917c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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