|Other Accession||NP_659442.2, NP_060795.1|
|Other Names||Protein C9orf72, C9orf72|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in endosomal trafficking and autophagy.|
|Cellular Location||Nucleus. Cytoplasm. Endosome. Lysosome. Cytoplasmic vesicle, autophagosome. Secreted. Note=Detected in the cytoplasm of neurons from post mortem brain tissue (PubMed:21944778). Detected in the nucleus in fibroblasts (PubMed:21944779).|
|Tissue Location||Both isoforms are widely expressed, including kidney, lung, liver, heart, testis and several brain regions, such as cerebellum. Also expressed in the frontal cortex and in lymphoblasts (at protein level).|
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Suarez-Gestal, M., et al. Arthritis Res. Ther. 12 (2), R72 (2010) :van Es, M.A., et al. Nat. Genet. 41(10):1083-1087(2009)Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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