|Other Names||Sodium channel and clathrin linker 1, Sodium channel-associated protein 1, SCLT1, SAP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane|
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Provided below are standard protocols that you may find useful for product applications.
SCLT1 acts as a linker protein between the voltage-gatedsodium channel Na(v)1.8 (SCN10A; MIM 604427) and clathrin (seeCLTC, MIM 118955) (Liu et al., 2005 [PubMed 15797711]).[supplied byOMIM].
Liu, C., et al. Mol. Cell. Neurosci. 28(4):636-649(2005)Tomarev, S.I., et al. Invest. Ophthalmol. Vis. Sci. 44(6):2588-2596(2003)
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